| 90's babe | Bibliophile | Dreamer | Nursing | Photography | E-book Collector | Techno-geek | Realist |

Read tons of novels and manga

Watched a lot of anime, drama movies and TV series ;)

Thomasian, Ednasian

Plans to go to Med school and travel the world someday :)

Fluffy haired ;)

  • "Give without remembering and always receive without forgetting."
  • "You can’t live a perfect day without doing something for someone who will never be able to repay you. -John Wooden"
  • Stress is killing me. I’ve got no proper sleep since last week. Mental facilities are nearing critical levels. Going dysfunctional. Lots of quizzes, exams, paperworks, lectures, make up classes.

    Now breaking down into pieces, crying myself to oblivion and sleep.

  • eventy-r:

    School is overwhelming. I’ve honestly never experienced such stress and sense of helplessness

  • medicinasanguis:

    anatomy ❤️

    I’ll be like this soon. 👋 social life 🔫

  • currentsinbiology:

    How stress tears us apart

    Why is it that when people are too stressed they are often grouchy, grumpy, nasty, distracted or forgetful? Researchers from the Brain Mind Institute (BMI) at EPFL have just highlighted a fundamental synaptic mechanism that explains the relationship between chronic stress and the loss of social skills and cognitive impairment. When triggered by stress, an enzyme attacks a synaptic regulatory molecule in the brain. This was revealed by a work published in Nature Communications.

    Carmen Sandi’s team went to look for answers in a region of the hippocampus known for its involvement in behavior and cognitive skills. In there, scientists were interested in a molecule, the nectin-3 cell adhesion protein, whose role is to ensure adherence, at the synaptic level, between two neurons. Positioned in the postsynaptic part, these proteins bind to the molecules of the presynaptic portion, thus ensuring the synaptic function. However, the researchers found that on rat models affected by chronic stress, nectin-3 molecules were significantly reduced in number.

    Michael A. van der Kooij, Martina Fantin, Emilia Rejmak, Jocelyn Grosse, Olivia Zanoletti, Celine Fournier, Krishnendu Ganguly, Katarzyna Kalita, Leszek Kaczmarek, Carmen Sandi. Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations. Nature Communications, 2014; 5: 4995 DOI: 10.1038/ncomms5995

    Carmen Sandi’s team at EPFL discovered an important synaptic mechanism in the effects of chronic stress. It causes the massive release of glutamate which acts on NMDA receptors, essential for synaptic plasticity. These receptors activate MMP-9 enzymes which, like scissors, cut the nectin-3 cell adhesion proteins. This prevents them from playing their regulatory role, making subjects less sociable and causing cognitive impairment. Credit: EPFL

  • humorinrecovery:

    When PTSD nightmares get suddenly worse, but I’m used to it